Dr. Seyed Alireza Salami, PhD.

Head of Industrial and Medicinal Cannabis Research Institute (IMCRI)

Email: asalami@ut.ac.ir; Mobile: +98-912 542 3816

Dr. Salami, an associate professor at University of Tehran, is an expert in biotechnology, genetics and the bioinformatics. He received his Ph.D. in “Genetics of Host-Pathogen Interactions from University of Tehran followed by a research Ph.D. sabbatical at University of Adelaide, CSIRO and a research fellowship at Wageningen University.

Research interests:

Seyed Alireza Salami has 15+ years of experience in bio-science industry and in academia. His interest to pharmaceutical industry and several years of experience in genetic manipulation and bioinformatics, led him to start two mega projects on medicinal herbs mainly Cannabis (CannOMICS) and Saffron (CrocOMICS) at his lab since 2010.


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1- Soorni, A., R. Fatahi, D.C. Haak, S.A. Salami, A. Bombarely. 2017. Assessment of Genetic Diversity and Population Structure in Iranian cannabis Germplasm. Nature, Scientific Reports. 7, 15668 (https://doi.org/10.1038/s41598-017-15816-5)

2- Borna, T., S.A. Salami, M. Shokrpour. 2017. High resolution melting curve analysis revealed SNPs in major cannabinoid genes associated with drug and non-drug types of cannabis. Biotechnology and Biotechnological Equipment. 31, 839-845 (https://doi.org/10.1080/13102818.2017.1333456)

3- Jalali, S., S.A. Salami, M. Sharifi, S. Sohrabi. 2019. Signaling compounds elicit expression of key genes in cannabinoid pathway and related metabolites in cannabis. Industrial Crops and Products. 133, 105-110 (https://doi.org/10.1016/j.indcrop.2019.03.004)

4- Baeeria, M., M. Rahimifard, S.M. Daghighi, F. Khan, S.A. Salami, S. Moini-Nodeh, H. Haghi-Aminjan, Z. Bayrami, F. Rezaee, M. Abdollahi. 2020. Cannabinoids as anti-ROS in aged pancreatic islet cells. Life Sciences. 256, 117969 (https://doi.org/10.1016/j.lfs.2020.117969)

5- Bachari, A., J. Piva Terrence, S. A. Salami, N. Jmashidi, N. Mantri. 2020. Roles of Cannabinoids in Melanoma: Evidence from In Vivo Studies. International Journal of Molecular Sciences. 21, 6040 (https://doi.org/10.3390/ijms21176040)

6- Salami,S.A. , F. Martinelli, A. Giovino, A. Bachari, N. Arad, N. Mantri. 2020. It Is Our Turn to Get Cannabis High: Put Cannabinoids in Food and Health Baskets. Molecules. 25(18): 4036 (https://doi.org/10.3390/molecules25184036)

7- Babaei, M., M. Shokrpour, M. Sharifi, S.A. Salami. 2021. Screening of different Iranian ecotypes of cannabis under water deficit stress. Scientia Horticulturae. 260, 108904 (https://doi.org/10.1016/j.scienta.2019.108904).

8- Hooshangi, MR., S. Hamed Haghi-Aminjan, M. Baeeri, M. Rahimifard, S. Hassani, M. Gholami, Momtaz, S.A. Salami, et al. 2021. Modification of the hemodynamic and molecular features of phosphine, a potent mitochondrial toxicant in the heart, by cannabidiol. Toxicology Mechanisms and Methods. 24;1-14 (doi: 10.1080/15376516.2021.1998851).

9- Mostafaei Dehnavi, M., A. Ebadi, A. Peirovi, G. Taylor, S. A. Salami. 2022. THC and CBD Fingerprinting of an Elite Cannabis Collection from Iran: Quantifying Diversity to Underpin Future Cannabis Breeding. Plants. 11, 129 (https://doi.org/10.3390/plants11010129).

10- Hesami, M.; Pepe, M.; Baiton, A.; Salami, S.A.; Jones, A.M.P. 2022. New Insight into Ornamental Applications of Cannabis: Perspectives and Challenges. Plants, 11, 2383. (https://doi.org/10.3390/plants11182383).

11- Tajik, T., Baghaei, K., Moghadam, V. E., Farrokhi, N., & Salami, S. A. 2022. Extracellular vesicles of cannabis with high CBD content induce anticancer signaling in human hepatocellular carcinoma. Biomedicine & Pharmacotherapy, 152, 113209 (https://doi.org/10.1016/j.biopha.2022.113209).


Some Other Selected Publications

12- Ahadi Dolatsara, E, S. Salami, M. Shokrpour, M. Naghavi. 2011. Metabolic engineering: an effective approach for optimal production of secondary metabolite compounds. Planta Medica. 77 – PB35.

13- Hassani M, Salami S.A., H. Abdollahi, l. Hamzaban. 2014. Expression of pathogenicityrelated genes of apples in response to attack of Erwinia amylovora. Acta Horticulturae. 1056, 303-306

14- Zand karimi, H., A. Ebadi, S.A. Salami, H. Alizade, N. Baisakh.2015. Analyzing the Expression Profile of AREB/ABF and DREB/CBF Genes under Drought and Salinity Stresses in Grape (Vitis vinifera L.). PLoS One. 10(7): e0134288.

15-Bakhtiarizadeh, M.R., M. J. Najafpanah, H. Mousapour, S.A. Salami. 2016. Versatility of different melting temperature (Tm) calculation software for robust PCR and Real-Time PCR oligonucleotides design. Gene Reports. 2:1-3.

16-Hassani M, Salami S.A., Nasiri, J., H. Abdollahi, Z. Ghahremani. 2016. Phylogenetic analysis of PR genes in some pome fruit species with the emphasis on transcriptional analysis and ROS response under Erwinia amylovora inoculation in apple. Genetica. 144(1):9-22.

17- Bakhtiarizadeh M.R., Hosseinpour, B., Arefnezhad, B., Shamabadi, N., Salami S.A.2016. In silico prediction of long intergenic non-coding RNAs in sheep. Genome. 59(4):263-75.

18-Moazzami, S.H., T. Rajabian, M. Ranjbar, S.A. Salami, N. Rahmani, A. Ghorbani. 2016. Fatty acid patterns of seed of some Salvia species from Iran-A chemotaxonomic approach. Chemistry and Biodiversity. 13(4):451-8.

19-Basij, M., Talebi, K., Ghadamyari, M., Hosseininaveh, V., & Salami, S. A. 2017. Status of resistance of Bemisia tabaci (Hemiptera: Aleyrodidae) to Neonicotinoids in Iran and detoxification by Cytochrome P450-dependent monooxygenases. Neotropical Entomology. 1-10.

20-Morshedloo, M. R., Craker, L. E., Salami, A., Nazeri, V., Sang, H., and Maggi, F. 2017. Effect of prolonged water stress on essential oil content, compositions and gene expression patterns of mono-and sesquiterpene synthesis in two oregano (Origanum vulgare L.) subspecies. Plant Physiology and Biochemistry. 111, 119-128.

21-Attaran, S., P. Abrishamchi, T. Rajabian, S.A. Salami. 2017. Enhanced phenolic acids production in regenerated shoot cultures of Salvia virgata Jacq. after elicitation with Ag ions, methyl jasmonate and yeast extract. Industrial Crops and Products. 103:81-88.

22-Vahedi, M., M. Kabiri, S.A.Salami, H. Rezadoost, M. Mirzaei, M.R.Kanani. 2018. Quantitative HPLC-based metabolomics of some Iranian Saffron (Crocus sativus L.) accessions. Industrial Crops and Products. 118:26-29.

23-Morshedloo, M.R., S.A.Salami, V. Nazeri, F. Maggi, L. Craker. 2018. Essential oil profile of oregano (Origanum vulgar L.) populations grown under similar soil and climate conditions. Industrial Crops and Products. 119:183-190.

24-Bakhtiarzadeh, M.R., M. Rahimi,A. Mohammadi-Sangcheshmeh, V. Shariati, S.A. Salami. PrESOgenesis: A two-layer multi-label predictor for identifying fertility-related proteins using support vector machine and pseudo amino acid composition approach. Nature, Scientific Reports. 8:9025.

25-Hosseinpour, B., S. Sepahvand, K. Kamali Aliabad, M.R.Bakhtiarzadeh, A. Imani, S.A. Salami. 2018. Transcriptome profiling of fully open flowers in a frost-tolerant almond genotype in response to freezing stress. Molecular Genetics and Genomics. 293:151-163.

26-Sadeghi, Y., S.A.Salami, P. Kananizadeh, S.H. Mozhgani, M.R. Pourmand. 2019. Real-Time PCR followed by high-resolution melting analysis-a new robust approach to evaluate SCCmec typing of methicillin-resistant Staphylococus aureus. Future Microbiology.14 (2).

27-Bakhtiarzadeh, M.R., S.A.Salami. 2019. Identification and expression analysis of long noncoding RNAs in fat-tail of sheep breeds. Genes, Genomes, Genetics. 9: 1263-1276.

28-Bakhtiarzadeh, M.R., A. Salehi, A. Alamouti, R. Abdollahi-Arpanahi, S.A.Salami. 2019. Deep transcriptome analysis using RNA-Seq suggests novel insights into molecular aspects of fat-tail metabolism in sheep. Nature, Scientific Reports. 9:903, 1-14.

29-Abdi, G., M. Shokrpour, S.A. Salami. 2019. Essential Oil Composition at Different Plant Growth Development of Peppermint (Mentha x piperita L.) Under Water Deficit Stress. Journal of Essential Oil Bearing Plants. 32:431-440.

30-Khaleghi, A., R. Naderi, C. Brunetti, B.E. Maserti, S.A. Salami, M. Babalar. 2019. Morphological, physiochemical and antioxidant responses of Maclura pomifera to drought stress. Nature, Scientific Reports. 9, 19250.

31-Shahani, M., J. Shakeri, M.E. Akbari, S.A. Salami…et al. 2019. Transcriptomic and proteomic approaches reveal biological basis of intraoperative radiotherapy-treated tumor bed modification in breast cancer patients: A pilot study. Journal of Proteomics. 212, 103596.

32- Pakbaz, Z., Sahraian, M.A., Noorbakhsh, F., Salami, S.A., Pourmand, M.R. 2020. Staphylococcal enterotoxin B increased severity of experimental model of multiple sclerosis. Microbial Pathogenesis. 18;142:104064.

33- Dastkar, E., A. Soleimani, H. Jafary, J.D. Alche, A. Bahari, M. Zeinalabedini, S.A.Salami. 2020. Differential expression of genes in olive leaves and buds of ON-versus OFF-crop trees. Nature, Scientific Reports. 10:15762.

34- Taheri-Dehkordi, A., R. Naderi, F. Martinelli, S.A. Salami. 2020. A robust workflow for indirect somatic embryogenesis and cormlet production in saffron (Crocus sativus L.) and its wild allies; C. caspius and C. speciosus. Heliyon 6: e05841.

35- Moradi, S., M. Kafi, S. Aliniaeifard, S.A.Salami, M. Shokrpour, C. Pedersen, M. Moosavi-Nezhad, Wróbel, and H. M. Kalaji. 2021. “Blue Light Improves Photosynthetic Performance and Biomass Partitioning toward Harvestable Organs in Saffron (Crocus sativus L.). Cells. 10(8): 1994.

36- Pesaraklu, A., T. Radjabian, S. A. Salami. 2021. Methyl jasmonate and Ag+ as effective elicitors for enhancement of phenolic acids contents in Salvia officinalis and Salvia verticillata, as two traditional medicinal plants. South African Journal of Botany. 141: 105-115.

37- Attaran Dowom, S., Abrishamchi, P., Radjabian, T., S.A. Salami. 2021. Elicitor-induced phenolic acids accumulation in Salvia virgata Jacq. hairy root cultures. Plant Cell, Tissue and Organ Culture. 148: 107–117.

38- Taheri, A., R. Naderi, F. Martinelli, S.A.Salami. 2021. Computational screening of miRNAs and their targets in saffron (Crocus sativus L.) by transcriptome mining. Planta. 254 (6): 117.

39- Eskandari, N., Senyuk, V., Moore, J., Kalik, Z., Luan, Q., Papautsky, I., Moshiri, A., Bocchetta, M., Salami, S.A. Oryan, Sh. et al. 2021. Molecular activation of the Kv11.1 channel reprograms EMT in colon cancer by inhibiting TGF signaling via activation of calcineurin. Cancers. 13, 6025.

40- Martinelli, F., Perrone, A. Yousefi, S. Papini, A. Castiglione, S. Guarino, F. Cicatelli, A. Aelaei, M., Arad, N., Gholami, M., S.A.Salami. 2021. Botanical, Phytochemical, Anti-Microbial and Pharmaceutical Characteristics of Hawthorn (Crataegus monogyna Jacq.), Rosaceae. Molecules. 26, 7266.